California Proposition 38 (2026), explained

This was on the California ballot on Tuesday, November 3, 2026. No recommendation, just what it does and both sides.

Results are still being counted. Check back soon.

Proposition 38State law · Citizen initiative

Immunotherapy research bonds

Explain it like I'm 5

California would borrow money to study how the immune system fights diseases and to develop possible treatments. It is like borrowing money for a large science project whose useful results are possible but not guaranteed.

Yes vote

California could issue $8.4 billion in general obligation bonds for immunology and immunotherapy research.

No vote

California could not issue these bonds for the research program.

The question to ask yourself

Is borrowing billions for possible medical breakthroughs worth the certain long-term repayment cost?

The case for

  • Could accelerate research into cancer and other serious diseases.
  • Provides stable funding when federal or private research funding is uncertain.
  • Research discoveries could benefit public health and California's research economy.

Backed by: Michael J. Fox Foundation, Alzheimer's Los Angeles, American Nurses Association California, Kidney Cancer Association, Gary K. Michelson, Michelson Medical Research Foundation, California Democratic Party, California Republican Party, AFSCME Local 3299

The case against

  • Creates substantial long-term state debt and interest costs.
  • Research does not guarantee cures, approved treatments, or a set timeline.
  • The measure directs a substantial share toward a specifically structured research institute rather than leaving all funds broadly competitive.

Opposed by: Robert R. Kaplan Ph.D.

Money
State bond repayment is estimated at about $500 million annually for roughly 25 years, although future research revenue could offset some costs.
Don't be misled
Claims that it guarantees cures or cheaper medicines are misleading because research results and their public benefits are uncertain.

Free account: 3 questions, no card. Your question will be waiting in the chat.

Written by ChatGPT, Claude, Gemini and Grok with web search, then checked against each other. See where they disagreed on California. Your sample ballot and the official voter guide are the final word. Look up your sample ballot.

Also on the California ballot

  1. Proposition 1Housing and veterans bonds
  2. Proposition 2Bigger rainy day fund
  3. Proposition 3Permanent high-income tax
  4. Proposition 4Allow public campaign funding
  5. Proposition 5Change recall replacement rules
  6. Proposition 37Second mortgages for new homes
  7. Proposition 39Voter ID and citizenship checks
  8. Proposition 40One-time billionaire wealth tax
  9. Proposition 41Spending limits and tax audits
  10. Proposition 42Ban new taxes on personal savings
  11. Proposition 43Two-thirds vote for local taxes
  12. Proposition 44Clinic mission-spending requirement
  13. Proposition 45Faster reviews for essential projects